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A synergistic combination with chemotherapy has been demonstrated to extend inhibition of tumor proliferation and migration

However, significant weight loss and lifestyle changes can impact emotional well-being, leading to mood fluctuations in some individuals

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The company said the FDA based its approval on results from a Phase 3 trial of more than 300 adults with obesity

It also eliminates the concept of other-than-temporary impairment and requires credit losses related to available-for-sale debt securities to be recorded through an allowance for credit losses rather than as a reduction in the amortized cost basis of the securities